Hornberger is a surname. Notable people with the surname include:
- Gerd Hornberger (1910–1988), Olympic German athlete who competed in the 1936 Summer Olympics
- H. Richard Hornberger (1924-1997), American writer and surgeon.
- Pete Hornberger, a fictional character played by Scott Adsit on the American television series 30 Rock
- Raymond Hornberger (1898–1976), American soccer player