Hotak is a Pashtun family name, and the name of the Hotaki dynasty. People with the surname Hotak or Hotaki include:
- Abdul Aziz Hotak (died 1717), second ruler of the Hotaki dynasty
- Ashraf Hotaki (died 1730), fourth ruler of the Hotaki dynasty
- Ghulan Mohammed Hotak, Taliban fighter who defected to the Interim Afghan Government
- Hamza Hotak (born 1991), Afghan cricketer
- Hussain Hotaki (died 1738), fifth and last ruler of the Hotaki dynasty
- Mahmud Hotaki (died 1725), third ruler of the Hotaki dynasty
- Mir Wais Hotak (1673–1715), founder of the Hotaki dynasty
- Musa Hotak, Afghan military leader and politician from Maidan Shar of Wardak Province