Hydroxylamine dehydrogenase

Hydroxylamine dehydrogenase (EC 1.7.2.6, HAO (ambiguous)) is an enzyme with systematic name hydroxylamine:ferricytochrome-c oxidoreductase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Hydroxylamine dehydrogenase
Identifiers
EC no.1.7.2.6
CAS no.9075-43-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
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MetaCycmetabolic pathway
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(1) hydroxylamine + H2O + 2 ferricytochrome c nitrite + 2 ferrocytochrome c + 5 H+
(2) hydroxylamine + ferricytochrome c nitric oxide + ferrocytochrome c + 3 H+

The enzymes from the nitrifying bacterium Nitrosomonas europaea and the methylotrophic bacterium Methylococcus capsulatus are hemoproteins.

References

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  1. ^ Rees MK (January 1968). "Studies of the hydroxylamine metabolism of Nitrosomonas europaea. I. Purification of hydroxylamine oxidase". Biochemistry. 7 (1): 353–66. doi:10.1021/bi00841a045. PMID 5758552.
  2. ^ Hooper AB, Terry KR (November 1979). "Hydroxylamine oxidoreductase of Nitrosomonas. Production of nitric oxide from hydroxylamine". Biochimica et Biophysica Acta. 571 (1): 12–20. doi:10.1016/0005-2744(79)90220-1. PMID 497235.
  3. ^ Hooper AB, Balny C (August 1982). "Reaction of oxygen with hydroxylamine oxidoreductase of Nitrosomonas: fast kinetics". FEBS Letters. 144 (2): 299–303. doi:10.1016/0014-5793(82)80658-3. PMID 7117545. S2CID 9726167.
  4. ^ Lipscomb JD, Hooper AB (August 1982). "Resolution of multiple heme centers of hydroxylamine oxidoreductase from Nitrosomonas. 1. Electron paramagnetic resonance spectroscopy". Biochemistry. 21 (17): 3965–72. doi:10.1021/bi00260a010. PMID 6289867.
  5. ^ Poret-Peterson AT, Graham JE, Gulledge J, Klotz MG (December 2008). "Transcription of nitrification genes by the methane-oxidizing bacterium, Methylococcus capsulatus strain Bath". The ISME Journal. 2 (12): 1213–20. doi:10.1038/ismej.2008.71. PMID 18650926.
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