Hypodermin C (EC 3.4.21.49, Hypoderma collagenase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
| Hypodermin C | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.49 | ||||||||
| CAS no. | 122191-36-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- Hydrolysis of proteins including native collagen at -Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment
This enzyme is isolated from the larva of a warble fly, Hypoderma lineatum.
References
edit- ^ Lecroisey A, Boulard C, Keil B (November 1979). "Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum". European Journal of Biochemistry. 101 (2): 385–93. doi:10.1111/j.1432-1033.1979.tb19730.x. PMID 230030.
- ^ Lecroisey A, Keil B (October 1985). "Specificity of the collagenase from the insect Hypoderma lineatum". European Journal of Biochemistry. 152 (1): 123–30. doi:10.1111/j.1432-1033.1985.tb09171.x. PMID 2995028.
- ^ Lecroisey A, Gilles AM, De Wolf A, Keil B (June 1987). "Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum". The Journal of Biological Chemistry. 262 (16): 7546–51. PMID 3034899.
External links
edit- Hypodermin+C at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
