In enzymology, a hyponitrite reductase is an enzyme that catalyzes the oxidation of hydroxylamine H
2
NOH
by the nicotinamide adenine dinucleotide cation (NAD+) into hyponitrous acid HON=NOH:

hyponitrite reductase
Identifiers
EC no.1.7.1.5
CAS no.9029-30-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
2 H
2
NOH
+ 2 NAD+ HON=NOH + 2 NADH + 2 H+

This systematic name of this enzyme class hydroxylamine:NAD+ oxidoreductase. It is also called NADH2:hyponitrite oxidoreductase.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. It employs one cofactor, metal.

References

edit
  • Medina A, Nicholas DJ (March 1957). "Hyponitrite reductase in Neurospora". Nature. 179 (4558): 533–4.