Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene.[5][6]

IFT74
Identifiers
AliasesIFT74, CCDC2, CMG-1, CMG1, intraflagellar transport 74, BBS20, BBS22, SPGF58, JBTS40
External IDsOMIM: 608040; MGI: 1914944; HomoloGene: 11831; GeneCards: IFT74; OMA:IFT74 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001099222
NM_001099223
NM_001099224
NM_025103
NM_001349928

NM_001290568
NM_026319

RefSeq (protein)

NP_001092692
NP_001092693
NP_001092694
NP_079379
NP_001336857

NP_001277497
NP_080595

Location (UCSC)Chr 9: 26.95 – 27.07 MbChr 4: 94.61 – 94.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BCMG1 is upregulated by umbilical vein endothelial cells during capillary morphogenesis.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000096872Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028576Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: intraflagellar transport 74 homolog (Chlamydomonas)".
  6. ^ a b Bell SE, Mavila A, Salazar R, Bayless KJ, Kanagala S, Maxwell SA, Davis GE (August 2001). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J. Cell Sci. 114 (Pt 15): 2755–73. doi:10.1242/jcs.114.15.2755. PMID 11683410.

Further reading

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