IQ motif and Sec7 domain 2 is a protein that in humans is encoded by the IQSEC2 gene .[ 5] [ 6]
Clinical significance
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^ a b c GRCh38: Ensembl release 89: ENSG00000124313 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041115 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: IQ motif and Sec7 domain 2" .^ Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (February 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" . DNA Res . 5 (1): 31–9. doi :10.1093/dnares/5.1.31 PMID 9628581 . ^ a b Shoubridge C, Tarpey PS, Abidi F, Ramsden SL, Rujirabanjerd S, Murphy JA, Boyle J, Shaw M, Gardner A, Proos A, Puusepp H, Raymond FL, Schwartz CE, Stevenson RE, Turner G, Field M, Walikonis RS, Harvey RJ, Hackett A, Futreal PA, Stratton MR, Gécz J (June 2010). "Mutations in the guanine nucleotide exchange factor gene IQSEC2 cause nonsyndromic intellectual disability" . Nat. Genet . 42 (6): 486–8. doi :10.1038/ng.588 . PMC 3632837 PMID 20473311 .
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