In enzymology, an inositol 4-methyltransferase (EC 2.1.1.129) is an enzyme that catalyzes the chemical reaction
| inositol 4-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.129 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- S-adenosyl-L-methionine + myo-inositol S-adenosyl-L-homocysteine + 1D-4-O-methyl-myo-inositol
Thus, the two substrates of this enzyme are S-adenosyl methionine and myo-inositol, whereas its two products are S-adenosylhomocysteine and 1D-4-O-methyl-myo-inositol.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase. Other names in common use include myo-inositol 4-O-methyltransferase, S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase, and myo-inositol 6-O-methyltransferase.
References
edit- Vernon DM, Bohnert HJ (1992). "A novel methyl transferase induced by osmotic stress in the facultative halophyte Mesembryanthemum crystallinum". EMBO J. 11 (6): 2077–85. PMC 556674. PMID 1600940.
- Wanek W; Richter A (1995). "Purification and characterization of myo-inositol 6-O-methyltransferase from Vigna umbellata Ohwi et Ohashi". Planta. 197: 427–434. doi:10.1007/bf00196663.
