Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.[3]
| ITLN2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | ITLN2, HL-2, HL2, intelectin 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 609874; HomoloGene: 135852; GeneCards: ITLN2; OMA:ITLN2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.[4]
See also
editReferences
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000158764 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Intelectin 2". Retrieved 2016-02-25.
- ^ Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT (March 2016). "Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition". The Journal of Biological Chemistry. 291 (11): 5596–610. doi:10.1074/jbc.M115.709212. PMC 4786701. PMID 26755729.
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