Isaacson is a surname meaning "son of Isaac", the Biblical figure. Notable people with the surname include:
- Bruce Isaacson (born 1956), American poet and publisher
- Caroline Isaacson (1900–1962), Australian journalist
- David Isaacson, American military officer
- Dean Isaacson (born 1941), American statistician
- Doug Isaacson (born 1957), American politician from Alaska
- Frederick Wootton Isaacson (1836–1898), English politician
- Jacob Isaacson (1911–1980), American composer and musician
- James Isaacson (born 1980), English rugby union football player
- Jason Isaacson (born 1971), American politician from Minnesota
- Jeff Isaacson (born 1983), American curler
- Judith Magyar Isaacson (1925–2015), Hungarian-American schoolteacher, academic administrator, and writer
- Leonard Isaacson (1925–2018), American chemist and composer
- Megan Isaacson, American gospel singer
- Michael Isaacson (born 1946), American composer
- Peter Isaacson (1920–2017), English-born Australian newspaper publisher and military pilot
- Rich Isaacson (born 1964), American music entrepreneur
- Richard A. Isaacson, American physicist
- Robert Isaacson (1927–1998), American art collector, dealer, and scholar
- Thorpe B. Isaacson (1898–1970), American leader in The Church of Jesus Christ of Latter-day Saints
- Walter Isaacson (born 1952), American author, columnist and CEO
This page lists people with the surname Isaacson.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.