Issei or Issey is a masculine Japanese given name. Notable people with the name include:

  • Issei Endō (遠藤 一星, born 1989), Japanese baseball player
  • Issei Futamata (二又 一成, born 1955), Japanese actor, voice actor and narrator
  • Issei Kato (加藤 壱盛, born May 28, 2003), Japanese association football player
  • Issei Kitagawa (北川 一成, born 1942), Japanese politician
  • Issei Koga (古賀 一成, born 1947), Japanese politician
  • Issei Nishikawa (西川 一誠, born 1945), Japanese politician
  • Issey Miyake (三宅 一生, 1938–2022), Japanese fashion designer
  • Issei Miyazaki (宮崎 一成, born 1971), Japanese voice actor
  • Issei Noro (野呂 一生, born 1957), Japanese jazz fusion guitarist
  • Issey Ogata (イッセー尾形, born 1952), Japanese actor and comedian
  • Issei Otake (大竹 壱青, born 1995), Japanese volleyball player
  • Issei Sagawa (佐川 一政, 1949–2022), Japanese criminal
  • Issei Suda (須田 一政, 1940–2019), Japanese photographer
  • Issei Tajima (田島 一成, born 1940), Japanese politician
  • Issei Takazaki (髙﨑 一生, born 1987), Japanese shogi player
  • Issei Tanaka (田仲 一成), Japanese writer
  • Issei Yamamoto (山本 一清, 1889–1959), Japanese astronomer
  • Issei Mamehara (豆原 一成, born 2002), Japanese singer and actor, member of JO1

Fictional character

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  • Issei Hyodo (兵藤一誠), a character from the light novel series High School DxD
  • Issei Matsukawa (松川 一静), a character from the manga and anime Haikyu!! with the position of middle blocker from Aoba Johsai High