Istiratumab (MM-141) is an experimental monoclonal antibody for the treatment of cancer. It is a bispecific antibody targeting IGF-1R and ErbB3.[1]

Istiratumab
Monoclonal antibody
Type?
SourceHuman
TargetIGF1R, ErbB3
Clinical data
Other namesMM-141
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC8802H13532N2392O2796S58
Molar mass199458.51 g·mol−1

It is in development by Merrimack Pharmaceuticals and was awarded orphan drug status for pancreatic cancer.[2]

References

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  1. ^ Alternative Names: MM-141. "Istiratumab - AdisInsight". Adisinsight.springer.com. Retrieved 2017-05-22.{{cite web}}: CS1 maint: numeric names: authors list (link)
  2. ^ "STATEMENT ON A NONPROPRIETARY NAME ADOPTED BY THE USAN COUNCIL : USAN (CD-106) ISTIRATUMAB" (PDF). Searchusan.ama-assn.org. Retrieved 2017-05-23.