Jānis Bērziņš or Yan Berzin (Russian: Ян Берзин) may refer to:
- Jānis Bērziņš (politician) (1889–1938), Soviet military official and politician
- Jānis Bērziņš (diplomat) (1881–1938), Soviet diplomat
- Jānis Bērziņš (basketball) (born 1993), Latvian basketball player
- Jānis Bērziņš (biathlete) (born 1984), Latvian Olympic biathlete