James Frazier may refer to:
- James B. Frazier (1856–1937), American politician, U.S. senator, governor of Tennessee
- James B. Frazier Jr. (1890–1978), American politician, U.S. representative
- James Frazier (conductor), American orchestral conductor
- J. J. Frazier, American basketball player
- James Frazier (academic administrator), dancer and dean of the Florida State University College of Fine Arts