James Pitts may refer to:
- James Pitts (VC), English recipient of the Victoria Cross
- James Pitts (American Patriot), Massachusetts merchant and American Patriot
- James Pitts (chemist), American chemist and researcher
- James E. Pitts, United States Navy admiral
- Jim Pitts, member of the Texas House of Representatives
- J.E. Pitts (James Edward Pitts), American poet, songwriter and musician