Jean Chmielewski is an American chemist who is the Alice Watson Kramer Distinguished Professor at Purdue University.[1] Her research considers drug discovery, nanobiotechnology and the cellular delivery of therapeutic agents.[1][2] She was awarded the 2025 American Chemical Society Francis P. Garvan–John M. Olin Medal.
Jean Chmielewski | |
|---|---|
| Alma mater | St. Joseph University Columbia University |
| Scientific career | |
| Institutions | University of Purdue University of California, Berkeley Rockefeller University |
| Thesis | Transaminase and racemase activity of pyridoxal/pryidoxamine enzyme analogs (1998) |
Education
editChmielewski received her Bachelor of Science degree at Saint Joseph's University in 1983.[citation needed] Her undergraduate research developed prostaglandin oligomerization. She moved to Columbia University for her graduate studies, where she developed biomimetic chemistry with Ronald Breslow.[3] She completed her National Institutes of Health (NIH) Postdoctoral Fellowship in 1990 at Rockefeller University and the University of California, Berkeley.[4] At Rockefeller, Chmielewski was awarded an NIH postdoctoral fellowship, and worked with Emil T. Kaiser on peptide fragment coupling. At the University of California, Berkeley, Chmielewski developed covalent methods to stabilize peptide conformations.[citation needed]
Career
editChmielewski began her tenure as a professor at Purdue University.[4] Her early work looked to transform enzyme inhibitors for HIV/AIDS.[5][6] She looks to create antibiotics that target intracellular pathogenic bacteria and agents that modulate drug efflux transporters.[7]
Achievements and awards
edit- 2001 Agnes Fay Morgan Research Award[8][9]
- 2008 Elected Fellow of the American Association for the Advancement of Science[10]
- 2011 Edward Leete Award in Organic Chemistry[11]
- 2015 Vincent du Vigneaud Award[12]
- 2017 Purdue University Herbert Newby McCoy Award[13]
- 2017 Stanley C. Israel Regional Award for Advancing Diversity in the Chemical Sciences[14]
- 2022 American Peptide Society Murray Goodman Award[15]
- 2025 American Chemical Society Francis P. Garvan–John M. Olin Medal[16]
References
edit- ^ a b "Dr. Jean Chmielewski". Purdue University Department of Chemistry. Retrieved May 28, 2024.
- ^ "Chmielewski". Weldon School of Biomedical Engineering - Purdue University. Retrieved 2024-05-17.
- ^ "Transaminase and racemase activity of pyridoxal/pryidoxamine enzyme analogs | WorldCat.org". search.worldcat.org. Retrieved 2024-08-28.
- ^ a b "Purdue University: Department of Chemistry: Chmielewski Research Group: Professor Jean Chmielewski". www.chem.purdue.edu. Retrieved 2024-05-17.
- ^ "NSF Award Search: Award # 9457372 - NSF Young Investigator: The Study of Enzyme Inhibition". www.nsf.gov. Retrieved 2024-08-28.
- ^ Chmielewski, Jean. "Dimerization Inhibitors of HIV-1 Protease and Integrase". grantome.com.
- ^ "Professor Chmielewski named Interim Dean - Purdue University Department of Chemistry". www.chem.purdue.edu. Retrieved 2024-05-16.
- ^ "Chmielewski, Jean – American Peptide Society". Retrieved 2024-08-28.
- ^ "Past Award Winners". Iota Sigma Pi. Retrieved 2024-08-28.
- ^ Lempinen, Edward W. (2008-12-19). "AAAS News and Notes". Science. 322 (5909): 1806–1810. doi:10.1126/science.322.5909.1806. ISSN 0036-8075.
- ^ "Leete Award". ACS Division of Organic Chemistry. Retrieved 2024-08-28.
- ^ "Vincent du Vigneaud Award – American Peptide Society". Retrieved 2024-08-28.
- ^ "EVPRP Annual Report 2016-2017 by Purdue University, Office of the Executive Vice President for Research and Partnerships - Issuu". issuu.com. 2018-02-26. Retrieved 2024-08-28.
- ^ "Stanley C. Israel Award for Advancing Diversity in the Chemical Sciences". ChemDiversity. 2020-08-05. Retrieved 2024-08-28.
- ^ "Awards – APS 2022". Retrieved 2024-08-28.
- ^ "ACS announces its 2025 National Award winners". Chemical & Engineering News. Retrieved 2024-08-28.