Jean Chmielewski is an American chemist who is the Alice Watson Kramer Distinguished Professor at Purdue University.[1] Her research considers drug discovery, nanobiotechnology and the cellular delivery of therapeutic agents.[1][2] She was awarded the 2025 American Chemical Society Francis P. Garvan–John M. Olin Medal.

Jean Chmielewski
Alma materSt. Joseph University
Columbia University
Scientific career
InstitutionsUniversity of Purdue
University of California, Berkeley
Rockefeller University
ThesisTransaminase and racemase activity of pyridoxal/pryidoxamine enzyme analogs (1998)

Education

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Chmielewski received her Bachelor of Science degree at Saint Joseph's University in 1983.[citation needed] Her undergraduate research developed prostaglandin oligomerization. She moved to Columbia University for her graduate studies, where she developed biomimetic chemistry with Ronald Breslow.[3] She completed her National Institutes of Health (NIH) Postdoctoral Fellowship in 1990 at Rockefeller University and the University of California, Berkeley.[4] At Rockefeller, Chmielewski was awarded an NIH postdoctoral fellowship, and worked with Emil T. Kaiser on peptide fragment coupling. At the University of California, Berkeley, Chmielewski developed covalent methods to stabilize peptide conformations.[citation needed]

Career

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Chmielewski began her tenure as a professor at Purdue University.[4] Her early work looked to transform enzyme inhibitors for HIV/AIDS.[5][6] She looks to create antibiotics that target intracellular pathogenic bacteria and agents that modulate drug efflux transporters.[7]

Achievements and awards

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References

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  1. ^ a b "Dr. Jean Chmielewski". Purdue University Department of Chemistry. Retrieved May 28, 2024.
  2. ^ "Chmielewski". Weldon School of Biomedical Engineering - Purdue University. Retrieved 2024-05-17.
  3. ^ "Transaminase and racemase activity of pyridoxal/pryidoxamine enzyme analogs | WorldCat.org". search.worldcat.org. Retrieved 2024-08-28.
  4. ^ a b "Purdue University: Department of Chemistry: Chmielewski Research Group: Professor Jean Chmielewski". www.chem.purdue.edu. Retrieved 2024-05-17.
  5. ^ "NSF Award Search: Award # 9457372 - NSF Young Investigator: The Study of Enzyme Inhibition". www.nsf.gov. Retrieved 2024-08-28.
  6. ^ Chmielewski, Jean. "Dimerization Inhibitors of HIV-1 Protease and Integrase". grantome.com.
  7. ^ "Professor Chmielewski named Interim Dean - Purdue University Department of Chemistry". www.chem.purdue.edu. Retrieved 2024-05-16.
  8. ^ "Chmielewski, Jean – American Peptide Society". Retrieved 2024-08-28.
  9. ^ "Past Award Winners". Iota Sigma Pi. Retrieved 2024-08-28.
  10. ^ Lempinen, Edward W. (2008-12-19). "AAAS News and Notes". Science. 322 (5909): 1806–1810. doi:10.1126/science.322.5909.1806. ISSN 0036-8075.
  11. ^ "Leete Award". ACS Division of Organic Chemistry. Retrieved 2024-08-28.
  12. ^ "Vincent du Vigneaud Award – American Peptide Society". Retrieved 2024-08-28.
  13. ^ "EVPRP Annual Report 2016-2017 by Purdue University, Office of the Executive Vice President for Research and Partnerships - Issuu". issuu.com. 2018-02-26. Retrieved 2024-08-28.
  14. ^ "Stanley C. Israel Award for Advancing Diversity in the Chemical Sciences". ChemDiversity. 2020-08-05. Retrieved 2024-08-28.
  15. ^ "Awards – APS 2022". Retrieved 2024-08-28.
  16. ^ "ACS announces its 2025 National Award winners". Chemical & Engineering News. Retrieved 2024-08-28.