John Gifford may refer to:
- John Gifford (writer) (1758–1818), English political writer
- John Hoskins Gifford (c. 1693–1744), British politician
- Jack Gifford (John F. Gifford, 1941–2009), American engineer and businessman
- Sir John Gifford, 2nd Baronet, of the Gifford baronets
- Rufus Gifford (John Rufus Gifford , born 1974), American diplomat
- John C. Gifford, naturalist whose name is commemorated by the John C. Gifford Arboretum at the University of Miami