John Kilpatrick may refer to:
- John Reed Kilpatrick (1889 –1960), American athlete, soldier, and sports businessperson
- Jack Frederick Kilpatrick (1915-1967), Cherokee composer
- Jack Kilpatrick (1917–1989), British hockey player and Olympic gold medalist
- John Kilpatrick (footballer) (born 1938), Australian rules footballer
- John Kilpatrick (politician) (fl. 1990), chairman of the Oklahoma Turnpike Authority and namesake of the John Kilpatrick Turnpike