John O'Rourke may refer to:
- John O'Rourke (baseball) (1849–1911), baseball player
- John O'Rourke (1809–87), author, priest
- John O'Rourke (footballer, born 1945) (1945–2016), English footballer
- John O'Rourke (politician) (1834–1882), American politician in Wisconsin and Nebraska
- John O'Rourke (Gaelic footballer) (born 1992), Irish Gaelic footballer
- John H. O'Rourke (1856–1929), Jesuit priest
- John O'Rourke, producer of the 1996 film The Pompatus of Love
- Jack O'Rourke (1928–2008), Australian rules footballer
This disambiguation page lists articles about people with the same name.
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