John Theurer Cancer Center (JTCC) at the Hackensack University Medical Center (HUMC), and part of the Hackensack Meridian Health (HMH), specializes in oncology services and treatments.[1] It is known for being the first site approved to use cell-based gene therapy to treat patients with certain types of large B-cell lymphoma who have not responded or relapsed after at least two other kinds of treatment; it initiated the first CAR T-cell therapy clinical trials and is a member of the NCI-approved Georgetown Lombardi Comprehensive Cancer Center. Other areas of concentration include bone marrow transplants, stem cell transplantation, lymphoma, leukemia, multiple myeloma, neuro-oncology, cutaneous malignancy, gastrointestinal, geriatric, head and neck, thoracic, urologic, breast, and gynecologic.[2] As of 2023, Andre Goy is chair and Chief Physician Officer.[3][4][5]
| John Theurer Cancer Center | |
|---|---|
| Geography | |
| Location | 92 2nd Street, Hackensack, New Jersey, United States |
| Organization | |
| Funding | Non-profit hospital |
| Type | Cancer treatment |
| Affiliated university | Hackensack University Medical Center
Georgetown Lombardi Comprehensive Cancer Center Memorial Sloan Kettering Cancer Center |
| Network | Hackensack Meridian Health |
| Links | |
| Lists | Hospitals in the United States |
Georgetown Lombardi Comprehensive Cancer Center affiliation
editIn 2019, JTCC received approval from the National Cancer Institute (NCI) as a member of the NCI-approved Georgetown Lombardi Comprehensive Cancer Center.[6] The partnership focuses on advancing research and treatment in breast cancer, cancer prevention and control, experimental therapeutics and molecular oncology.[7][8][9] The Georgetown Lombardi Comprehensive Center is designated by the National Cancer Institute as a leader in cancer treatment.[10]
Hackensack University Medical Center and Hackensack Meridian Health affiliations
editJTCC is part of Hackensack University Medical Center. HUMC and part of the Hackensack Meridian Health network, which includes Joseph M. Sanzari Children's Hospital, the Cancer Center, a branch of The Betty Torricelli Institute for Breast Care, Ocean Medical Center, Pascack Valley Medical Center, and the Riverview Medical Center.[11][12][13]
In 2022, JTCC expanded its program to Hackensack Meridian Jersey Shore University Medical Center's HOPE Tower, providing access to specialized cancer services and access to clinical trials.[14]
Other affiliations
editJTCC has a partnership with Memorial Sloan Kettering Cancer Center (MSK) to provide cancer care and develop joint standards of care through the oversight of a governing board composed of members from both MSK and HMH.[15]
In 2021, JTCC entered into a clinical affiliation with Regional Cancer Care Associates (RCCA) to open a practice called Toms River Regional Cancer Center in Toms River, NJ. The center provides comprehensive medical and surgical oncology/hematology consultative services by community-based, regional, and national specialists for various types and stages of cancer and serious blood disorders.[13]
In 2022, JTCC entered into a clinical affiliation with St. Joseph's Health to provide expanded cancer care services to the residents of Wayne, Paterson, and Totowa.
Green initiatives
editIn 2011, JTCC at HUMC opened a $130-million, 155,000-sq. ft. facility.[1] The JTCC pavilion was built with a green roof, providing patients and visitors with a relaxing environment[16] and doubling as exterior insulation—greatly reducing heat gain and loss.[17] This reduces energy use for heating and cooling as well as harmful emissions.[18]
Notable accomplishments
edit- JTCC initiated the first CAR T-cell therapy clinical trials through its NCI collaboration and became the first certified center in New Jersey to offer this treatment, in which a patient's own immune cells (T-cells) are trained to fight cancer.[19]
- JTCC supports the Northeast's largest bone marrow transplant (BMT) program and, in 2014, performed 400 transplants.[8]
- Treated first US patient with an investigatory drug for relapsed glioblastoma and other anaplastic gliomas.[20][21]
- First to use a biomarker surveillance program that screens patients who are at high-risk for developing pancreatic cancer.[22]
- Among the first of limited U.S. sites approved to offer Yescarta (axicabtagene ciloleucel), a cell-based gene therapy, to treat adult patients with certain types of large B-cell lymphoma who have not responded or relapsed after at least two other kinds of treatment.[23] As of 2023, it is also approved for all six commercially available CAR-T products for lymphoma, multiple myeloma and pediatric B-Cell precursor acute lymphoblastic leukemia: Yescarta, Tecartus (brexucabtagene autoleucel), Breyanzi (lisocabtagene maraleucel), Carvykti (ciltacabtagene autoleucel), Abecma (idecabtagene vicleucel), and Kymriah (tisagenlecleucel).
References
edit- ^ a b "Hackensack Meridian John Theurer Cancer Center". Retrieved 2022-03-26.
- ^ "Hackensack, NJ". Regional Cancer Care Associates. Retrieved 2022-11-17.
- ^ Goy, Andre (2022-11-14). "Andre H. Goy, MD, on Unresolved Questions in Mantle Cell Lymphoma". Oncology. 36 (11): 651–653.
- ^ "Dr Andre Goy on Predictive Biomarker Use for CAR T-Cell Therapy Response in Patients With Large B-Cell Lymphoma". AJMC. 12 December 2021. Retrieved 2022-02-22.
- ^ "Andre Goy, MD, Appointed Physician-in-Chief to Lead Cancer Care Across Hackensack Meridian Health Network". OncLive. 18 June 2020. Retrieved 2023-04-11.
- ^ "NCI approves Georgetown-Hackensack consortium". The Cancer Letter. 2019-05-10. Retrieved 2021-08-27.
- ^ Vecchione, Anthony (2019-05-07). "NCI approves John Theurer Cancer Center as research consortium member". NJBIZ. Retrieved 2021-08-27.
- ^ a b "NCI Approves John Theurer Cancer Center as Member of Research Consortium - The ASCO Post". ascopost.com. Retrieved 2021-08-27.
- ^ Washburn, Lindy. "New cancer treatment options in Passaic County from health system partnership". North Jersey Media Group. Retrieved 2023-02-22.
- ^ "Georgetown Lombardi Comprehensive Cancer Center - NCI". www.cancer.gov. 2012-07-26. Retrieved 2023-03-22.
- ^ "Small numbers of cells in a tumor could be key enablers of cancer metastasis". EurekAlert!. Retrieved 2022-02-22.
- ^ "St. Joseph's Health and Hackensack Meridian Health: Affiliation Brings More Advanced Cancer Care To Northern New Jersey". TAPinto. Retrieved 2023-03-04.
- ^ a b "Hackensack Meridian Health John Theurer Cancer Center (JTCC) creates affiliation with Regional Cancer Care Associates (RCCA) in Toms River, NJ". Shore News Network. 2021-03-30. Retrieved 2023-04-13.
- ^ Ebenau, Vin (3 May 2022). "Jersey Shore University Medical Center now has expansive cancer care center with easier access for Ocean and Monmouth residents". 92.7 WOBM. Retrieved 2023-04-11.
- ^ "Memorial Sloan Kettering and Hackensack Meridian Health". Sloan Kettering. Retrieved November 17, 2022.
- ^ "Psychological Benefit of Green Roofs" (PDF). Ohio.edu. Retrieved March 21, 2023.
- ^ "Does a green roof have an insulating effect? - Sempergreen". www.sempergreen.com. Retrieved 2023-03-21.
- ^ "John Theurer Cancer Center at the Hackensack University Medical Center - Greenroofs.com". Greenroofs.com. Retrieved 2022-11-17.
- ^ "John Theurer Cancer Center Recognized by US News & World Report". New Jersey Business Magazine. Retrieved 2023-04-13.
- ^ Lindner, Linda (2022-03-29). "John Theurer Cancer Center treats 1st patient in U.S. with investigational drug for brain cancer". ROI-NJ. Retrieved 2022-11-17.
- ^ Tiek, Deanna M.; Erdogdu, Beril; Razaghi, Roham; Jin, Lu; Sadowski, Norah; Alamillo-Ferrer, Carla; Hogg, J. Robert; Haddad, Bassem R.; Drewry, David H.; Wells, Carrow I.; Pickett, Julie E.; Song, Xiao; Goenka, Anshika; Hu, Bo; Goldlust, Samuel A. (2022-06-24). "Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas". Science Advances. 8 (25): eabn3471. Bibcode:2022SciA....8N3471T. doi:10.1126/sciadv.abn3471. ISSN 2375-2548. PMC 9216507. PMID 35731869.
- ^ NJBIZ (2022-04-28). "Hackensack UMC unveils new pancreatic cancer test". NJBIZ. Retrieved 2022-11-17.
- ^ "John Theurer Cancer Center First NJ Site Certified to offer CAR-T Cell Cancer Therapy". OncLive. 9 March 2018. Retrieved 2022-11-17.