Julie Angela Segre is the Chief and Senior Investigator of the Translational and Functional Genomics Branch in the National Human Genome Research Institute at the National Institutes of Health.[4] She was elected to the National Academy of Medicine in 2019,[5] the American Academy of Arts and Sciences in 2020[6] and the National Academy of Sciences in 2022.[7]

Julie A. Segre
Photo of Julie Segre
Julie A. Segre, Ph.D. Senior Investigator, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH).
Born
Alma mater
Known for
  • Foundational studies of the human skin associated microbes (bacteria, fungi, viruses)skin flora[1]
  • Using DNA sequencing to track antibiotic-resistant bacteria in hospitals.

[2]

  • NIH 'superbug' was thwarted with help of two scientists

[3]

Scientific career
Fields
  • Microbial Genomics
  • Genetics and Molecular Biology
Institutions
Academic advisorsEric Lander, Elaine Fuchs

Early life and education

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Segre was born in Berkeley, California, the daughter of Nina and Gino Claudio Segrè. She was raised in Philadelphia, where her father was a professor of physics at the University of Pennsylvania. Segre received her B.A. summa cum laude in mathematics from Amherst College in 1987,[8] where she later served on the board of trustees.[9] She received her Ph.D. in 1996 from the Massachusetts Institute of Technology. Segre then performed postdoctoral training in Molecular Genetics and Cell Biology at the University of Chicago (1996-2000).

Research and career

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Segre came to the National Human Genome Research Institute of NIH in 2000 and was promoted to a senior investigator with tenure in 2007.[10]

Segre's laboratory studies how the epidermis interfaces between the body and the environment.[11] Using genomic methodologies, Segre studies the bacteria and microbes of the skin microbiome.[11] Segre's laboratory also develops genomic tools to track hospital-acquired infections of multi-drug resistant organisms. [12] [13]

Medical and research achievements

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References

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  1. ^ Byrd, A. L.; Belkaid, Y.; Segre, J. A. (2018). "The human skin microbiome". Nature Reviews. Microbiology. 16 (3): 143–155. doi:10.1038/nrmicro.2017.157. PMID 29332945. S2CID 46781506.
  2. ^ Zimmer, Carl. "How Scientists Stalked a Lethal Superbug—With the Killer's Own DNA". Wired.
  3. ^ "NIH 'superbug' was thwarted with help of two scientists". The Washington Post.
  4. ^ "Julie Segre biography".
  5. ^ "National Academy of Medicine". 21 October 2019.
  6. ^ "New Members". American Academy of Arts & Sciences. Retrieved 2020-04-23.
  7. ^ "National Academy of Sciences". 3 May 2022.
  8. ^ Women in Science at National Institutes of Health 2007-2008. U.S. Department of Health and Human Services. pp. 63–64.
  9. ^ "Amherst Trustees".
  10. ^ "NHGRI genome.gov".
  11. ^ a b "NIH Intramural Research Program".
  12. ^ Johnson, Ryan C.; Deming, Clay; Conlan, Sean; Zellmer, Caroline J.; Michelin, Angela V.; Lee-Lin, Shihqueen; Thomas, Pamela J.; Park, Morgan; Weingarten, Rebecca A.; Less, John; Dekker, John P.; Frank, Karen M.; Musser, Kimberlee A.; McQuiston, John R.; Henderson, David K.; Lau, Anna F.; Palmore, Tara N.; Segre, Julia A. (2018). "Investigation of a Cluster of Sphingomonas koreensis Infections". New England Journal of Medicine. 379 (26): 2529–2539. doi:10.1056/NEJMoa1803238. PMC 6322212. PMID 30586509.
  13. ^ Conlan, Sean; Thomas, Pamela J.; Deming, Clayton; Park, Morgan; Lau, Anna F.; Dekker, John P.; Snitkin, Evan S.; Clark, Tyson A.; Luong, Khai; Song, Yi; Tsai, Yu-Chih; Boitano, Matthew; Dayal, Jyoti; Brooks, Shelise Y.; Schmidt, Brian; Young, Alice C.; Thomas, James W.; Bouffard, Gerard G.; Blakesley, Robert W.; Mullikin, James C.; Korlach, Jonas; Henderson, David K.; Frank, Karen M.; Palmore, Tara N.; Segre, Julia A.; Segre, J. A. (2014). "Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae". Science Translational Medicine. 6 (254): 254ra126. doi:10.1126/scitranslmed.3009845. PMC 4203314. PMID 25232178.
  14. ^ Samuel J. Heyman Service to America Medals. "2013 Federal Employees of the Year". Partnership for Public Service. Archived from the original on 2 April 2015. Retrieved 15 March 2015.
  15. ^ "Federal 'Employee of the Year' Honorees Hail from NIH".
  16. ^ "79 Fellows elected to the American Academy of Microbiology".
  17. ^ "National Academy of Medicine". 21 October 2019.
  18. ^ "New Members". American Academy of Arts & Sciences. Retrieved 2020-04-23.
  19. ^ "National Academy of Sciences". 3 May 2022.
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