The K10 transport/localisation element (TLS) is a 44 nucleotide K10 TLS regulatory element from Drosophila melanogaster. K10 TLS is responsible for the transport and anterior localisation of K10 mRNA and acts to establish dorsoventral polarity in the oocyte.[1][2] It was discovered by Julia Serano.
| K10 transport/localisation element (TLS) | |
|---|---|
 Predicted secondary structure and sequence conservation of K10_TLS | |
| Identifiers | |
| Symbol | K10_TLS |
| Rfam | RF00207 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Eukaryota |
| SO | SO:0005836 |
| PDB structures | PDBe |
References
edit- ^ Serano TL, Cohen RS (November 1995). "A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA". Development. 121 (11): 3809–3818. doi:10.1242/dev.121.11.3809. PMID 8582290.
- ^ Guillemin K, Williams T, Krasnow MA (September 2001). "A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila". Nature Cell Biology. 3 (9): 848–851. doi:10.1038/ncb0901-848. PMID 11533666. S2CID 15530627.
External links
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