Lysine demethylase 8 is a protein that in humans is encoded by the KDM8 gene.[5]
Function
editThis gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000155666 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030752 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Lysine demethylase 8". Retrieved 2016-04-09.
Further reading
edit- Suzuki T, Minehata K, Akagi K, Jenkins NA, Copeland NG (2006). "Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice". EMBO J. 25 (14): 3422–31. doi:10.1038/sj.emboj.7601215. PMC 1523184. PMID 16858412.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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