KIAA1949

Phostensin is a protein that in humans is encoded by the KIAA1949 gene.

PPP1R18
Identifiers
Aliases	PPP1R18, HKMT1098, KIAA1949, protein phosphatase 1 regulatory subunit 18
External IDs	OMIM: 610990; MGI: 1923698; HomoloGene: 19512; GeneCards: PPP1R18; OMA:PPP1R18 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.33 Start 30,676,389 bp End 30,687,895 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 B1 Start 36,176,485 bp End 36,186,488 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood lymph node spleen monocyte appendix right coronary artery Descending thoracic aorta ascending aorta bone marrow Top expressed in granulocyte mesenteric lymph nodes tibiofemoral joint thymus blood spleen stroma of bone marrow Ileal epithelium lactiferous gland subcutaneous adipose tissue More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 170954 76448 Ensembl ENSG00000229998 ENSG00000230341 ENSG00000225060 ENSG00000236428 ENSG00000146112 ENSG00000206485 ENSG00000231247 ENSG00000234000 ENSMUSG00000034595 UniProt Q6NYC8 Q8BQ30 RefSeq (mRNA) NM_001134870 NM_133471 NM_001146710 NM_001146711 NM_175242 NM_001378889 RefSeq (protein) NP_001128342 NP_597728 NP_001140182 NP_001140183 NP_780451 NP_001365818 Location (UCSC) Chr 6: 30.68 – 30.69 Mb Chr 17: 36.18 – 36.19 Mb PubMed search
Wikidata
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Further reading

• Kao SC, Chen CY, Wang SL, et al. (2007). "Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit". Biochem. Biophys. Res. Commun. 356 (3): 594–8. doi:10.1016/j.bbrc.2007.03.026. PMID 17374523.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Yamada S, Ohira M, Horie H, et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene. 23 (35): 5901–11. doi:10.1038/sj.onc.1207782. PMID 15221005. S2CID 3114318.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.