KIF20B

Kinesin family member 20B is a protein that in humans is encoded by the KIF20B gene.

KIF20B
Identifiers
Aliases	KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1, kinesin family member 20B
External IDs	OMIM: 605498; MGI: 2444576; HomoloGene: 9418; GeneCards: KIF20B; OMA:KIF20B - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q23.31 Start 89,701,590 bp End 89,774,939 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 C1 Start 34,899,761 bp End 34,953,145 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle oocyte secondary oocyte gonad ventricular zone Achilles tendon ganglionic eminence trabecular bone bone marrow cells skin of thigh Top expressed in genital tubercle tail of embryo secondary oocyte zygote hand ventricular zone primary oocyte spermatocyte lumbar spinal ganglion morula More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding microtubule motor activity protein homodimerization activity microtubule binding ATPase activity protein binding WW domain binding plus-end-directed microtubule motor activity ATP binding Cellular component cytoplasm centrosome mitotic spindle pole cell projection spindle pole contractile ring kinesin complex growth cone microtubule cytoskeleton spindle nucleoplasm microtubule organizing center mitotic spindle midzone axon midbody nucleolus spindle midzone perinuclear region of cytoplasm microtubule cytoskeleton nucleus Biological process positive regulation of intracellular protein transport neuron projection morphogenesis cell division positive regulation of cytokinesis positive regulation of neuron migration microtubule-based movement positive regulation of mitotic cytokinetic process neural tube closure protein localization to microtubule regulation of establishment of protein localization positive regulation of cell population proliferation regulation of neuron migration cell cycle regulation of establishment of cell polarity regulation of mitotic nuclear division Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9585 240641 Ensembl ENSG00000138182 ENSMUSG00000024795 UniProt Q96Q89 Q80WE4 RefSeq (mRNA) NM_016195 NM_001284259 NM_001382506 NM_183046 NM_001362434 RefSeq (protein) NP_001271188 NP_057279 NP_001369435 NP_898867 NP_001349363 Location (UCSC) Chr 10: 89.7 – 89.77 Mb Chr 19: 34.9 – 34.95 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Interactions

KIF20B has been shown to interact with PIN1.

Further reading

• Fritzler MJ, Kerfoot SM, Feasby TE, et al. (2000). "Autoantibodies from patients with idiopathic ataxia bind to M-phase phosphoprotein-1 (MPP1)". J. Investig. Med. 48 (1): 28–39. PMID 10695267.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Abaza A, Soleilhac JM, Westendorf J, et al. (2003). "M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis". J. Biol. Chem. 278 (30): 27844–52. doi:10.1074/jbc.M304522200. PMC 2652640. PMID 12740395.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.