KIFC3

Kinesin-like protein KIFC3 is a protein that in humans is encoded by the KIFC3 gene.

KIFC3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2H58
Identifiers
Aliases	KIFC3, kinesin family member C3
External IDs	OMIM: 604535; MGI: 109202; HomoloGene: 124421; GeneCards: KIFC3; OMA:KIFC3 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16q21 Start 57,758,217 bp End 57,863,053 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8 C5|8 47.12 cM Start 95,826,456 bp End 95,929,440 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland sural nerve body of pancreas right testis left testis skin of leg apex of heart right lobe of liver upper lobe of left lung Top expressed in right kidney right ventricle lip spermatocyte spermatid molar islet of Langerhans morula myocardium of ventricle adrenal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function microtubule motor activity nucleotide binding microtubule binding minus-end-directed microtubule motor activity ATPase activity protein binding ATP binding Cellular component cytoplasm centrosome Golgi apparatus membrane adherens junction microtubule organizing center cell junction zonula adherens microtubule extracellular exosome cytoplasmic vesicle membrane cytoskeleton cytoplasmic vesicle kinesin complex Biological process Golgi organization epithelial cell-cell adhesion microtubule-based movement zonula adherens maintenance microtubule-based process visual perception Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3801 16582 Ensembl ENSG00000140859 ENSMUSG00000031788 UniProt Q9BVG8 O35231 RefSeq (mRNA) NM_001130099 NM_001130100 NM_005550 NM_001318710 NM_001318711 NM_001318712 NM_001318713 NM_001318714 NM_001318715 NM_001145831 NM_001145832 NM_010631 NM_001372312 NM_001372313 NM_001372314 NM_001372315 NM_001372316 NM_001372317 RefSeq (protein) NP_001123571 NP_001123572 NP_001305639 NP_001305640 NP_001305641 NP_001305642 NP_001305643 NP_001305644 NP_005541 NP_001139303 NP_001139304 NP_034761 NP_001359241 NP_001359242 NP_001359243 NP_001359244 NP_001359245 NP_001359246 Location (UCSC) Chr 16: 57.76 – 57.86 Mb Chr 8: 95.83 – 95.93 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Diu A, Moebius U, Ferradini L, et al. (1993). "Limited T-cell receptor diversity in liver-infiltrating lymphocytes from patients with primary biliary cirrhosis". J. Autoimmun. 6 (5): 611–9. doi:10.1006/jaut.1993.1050. PMID 8240664.
• Hoang E, Bost-Usinger L, Burnside B (1999). "Characterization of a novel C-kinesin (KIFC3) abundantly expressed in vertebrate retina and RPE". Exp. Eye Res. 69 (1): 57–68. doi:10.1006/exer.1999.0671. PMID 10375449.
• Noda Y, Okada Y, Saito N, et al. (2001). "KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes". J. Cell Biol. 155 (1): 77–88. doi:10.1083/jcb.200108042. PMC 2150803. PMID 11581287.
• Xu Y, Takeda S, Nakata T, et al. (2002). "Role of KIFC3 motor protein in Golgi positioning and integration". J. Cell Biol. 158 (2): 293–303. doi:10.1083/jcb.200202058. PMC 2173137. PMID 12135985.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Roni V, Carpio R, Wissinger B (2007). "Mapping of transcription start sites of human retina expressed genes". BMC Genomics. 8: 42. doi:10.1186/1471-2164-8-42. PMC 1802077. PMID 17286855.

External links

• Overview of all the structural information available in the PDB for UniProt: Q9BVG8 (Human Kinesin-like protein KIFC3) at the PDBe-KB.