KRT75 is a keratin gene involved in hair shaft structure in mice.[1] In chickens, mutations in KRT75 cause animals to have frizzled feathers.[2]
| keratin 75 | |
|---|---|
| Identifiers | |
| Symbol | KRT75 |
| NCBI gene | 9119 |
| HGNC | 24431 |
| RefSeq | NM_004693 |
| Other data | |
| Locus | Chr. 12 q13 |
References
edit- ^ Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J (January 2016). "Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75". The Journal of Investigative Dermatology. 136 (1): 45–51. doi:10.1038/JID.2015.375. PMC 4764097. PMID 26763422.
- ^ Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF, Leal SM, Zhang H, Widelitz RB, Patel PI, Li WH, Chuong CM (2012). "The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis". PLOS Genetics. 8 (7): e1002748. doi:10.1371/journal.pgen.1002748. PMC 3400578. PMID 22829773.
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