Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene .[ 5] [ 6]
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells , forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000170423 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050463 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins" . J Cell Biol . 174 (2): 169–74. doi :10.1083/jcb.200603161 . PMC 2064177 PMID 16831889 . ^ a b "Entrez Gene: KRT78 keratin 78" .
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