Kalkadoon may refer to:
- Kalkadoon, Queensland, a suburb of Mount Isa, north-west Queensland, Australia
- Kalkatungu people, also known as the Kalkadoon people, an indigenous Australian tribe of the Mount Isa region
- Kalkatungu language, also known as the Kalkadoon language, now extinct
- Kalkadoon Wars, a series of late 19th century hostile encounters between the Kalkadoon people and European settlers
- Kalkadoon grasswren (Amytornis ballarae), a species of small bird endemic to north-west Queensland