Karen Elizabeth Keitley Duff (born 1965) is a British scientist known for her work on Alzheimer's disease. Her most notable work focused on the development and characterization of mouse models of Alzheimer's disease amyloid deposition.[1][2] She became Centre Director of the UK Dementia Research Institute's hub at University College London in spring 2020.[3]
Karen Duff | |
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| Born | 1965 (age 58–59) |
| Alma mater | University of East Anglia Queens' College, Cambridge |
| Awards | Potamkin Prize (2006) |
| Scientific career | |
| Fields | Pathology Cell Biology |
| Institutions | University College London Columbia University New York University University of South Florida |
| Thesis | A study of human and murine cardiac development using molecular genetics methodology (1991) |
| Website | Karen Duff |
She was educated at the University of East Anglia (BSc, 1987) and completed her PhD at Queens' College, Cambridge in 1991. At Cambridge she was a student of Sydney Brenner's department. She was awarded the Potamkin Prize in 2006, together with Karen Ashe and Bradley Hyman.[4] In 2020 she was awarded the British Neuroscience Association Award for Outstanding Contribution to Neuroscience.[5] She was formerly Professor of Pathology and Cell Biology at Columbia University.[6]
She has an h-index of 96 according to Google Scholar.[7]
References
edit- ^ Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K (January 1998). "Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes". Nat Med. 4 (1): 97–100. doi:10.1038/nm0198-097. PMID 9427614. S2CID 22491239.
- ^ Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S (October 1996). "Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1". Nature. 383 (6602): 710–3. Bibcode:1996Natur.383..710D. doi:10.1038/383710a0. PMID 8878479. S2CID 4339658.
- ^ "Right drug, right patient, right time: Unravelling clinical trial failures in dementia with Professor Karen Duff". UK Dementia Research Institute. Retrieved 4 February 2021.
- ^ "Karen Duff Receives Prestigious Prize for Alzheimer's Research". NYU Langone Medical Center. Retrieved 6 August 2014.
- ^ "Prizes awarded by the British Neuroscience Association | The British Neuroscience Association". www.bna.org.uk. Retrieved 29 April 2021.
- ^ "Karen Duff, Ph.D. - Professor of Pathology & Cell Biology". Columbia University. Retrieved 6 August 2014.
- ^ "karen duff". Google Scholar. Retrieved 14 April 2024.
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