Karle is a given name and surname.
Notable persons
editGiven name
edit- Karle Wilson Baker (1878–1960), American author
- Karle Carder-Andrews (born 1989), English football player
- Karle Hammond (born 1974), English rugby player
- Karle Warren (born 1992), American actress
Surname
edit- Charles Karle (1898–1946), American rower
- Isabella Karle (1921–2017), American physical chemist
- Jerome Karle (1918–2013), American physical chemist
- John L. Karle (1894–1953), American lawyer and politician