Kathleen Jacobs Kelly (born 1954) is an American biologist specializing in genetic regulation of cell growth, cancer progression, and metastasis. She is chief of the laboratory of genitourinary cancer pathogenesis (LGCP) and deputy director of the National Cancer Institute Center for Cancer Research.
Kathleen Kelly | |
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| Born | 1954 (age 69–70) |
| Alma mater | University of California, Irvine (PhD) |
| Scientific career | |
| Fields | Cancer biology |
| Institutions | National Cancer Institute |
| Thesis | Genetic and biochemical aspects of B lymphocytes responses to bacterial lipopolysaccharides (1980) |
Education
editKelly earned a Ph.D. degree from the University of California, Irvine.[1] Her 1980 dissertation was titled Genetic and biochemical aspects of B lymphocytes responses to bacterial lipopolysaccharides.[2] She completed postdoctoral training in the laboratory of Philip Leder, Harvard Medical School.[1]
Career
editKelly has maintained an independent research program at the National Cancer Institute (NCI) since 1984. She is chief of the laboratory of genitourinary cancer pathogenesis (LGCP) and deputy director of the NCI Center for Cancer Research.[3][1]
Research
editKelly's interests have focused on the genetic regulation of cell growth, cancer progression and metastasis. Her program investigates mechanisms of prostate cancer tumorigenesis and progression. A major area of focus addresses the roles of oncogenotype, tumor heterogeneity/cancer stem cells, and metabolism in the development of therapeutic responses, especially for castrate resistant prostate cancer. Additional research investigates signal transduction pathways that influence prostate cancer bone metastasis. As chief of LGCP, Kelly advances integration with the clinical prostate cancer program to carry out mechanism-based translational research using a variety of pathological, genomic, and patient-derived live culture approaches.[1]
References
edit- ^ a b c d "Kathleen Kelly, Ph.D." Center for Cancer Research. 2014-08-12. Retrieved 2020-10-04.
This article incorporates text from this source, which is in the public domain.
- ^ Kelly, Kathleen Jacobs (1980). Genetic and biochemical aspects of B lymphocytes responses to bacterial lipopolysaccharides (Ph.D. thesis). University of California, Irvine. OCLC 364912039.
- ^ "Principal Investigators". NIH Intramural Research Program. Retrieved 2020-10-04. This article incorporates text from this source, which is in the public domain.
This article incorporates public domain material from websites or documents of the National Institutes of Health.External links
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