Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene.[5][6]

KLHL12
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKLHL12, C3IP1, DKIR, hDKIR, kelch like family member 12
External IDsOMIM: 614522; MGI: 2385619; HomoloGene: 23317; GeneCards: KLHL12; OMA:KLHL12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001303051
NM_001303109
NM_021633

NM_153128
NM_001311136

RefSeq (protein)

NP_001289980
NP_001290038
NP_067646

NP_001298065
NP_694768

Location (UCSC)Chr 1: 202.89 – 202.93 MbChr 1: 134.38 – 134.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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KLHL12 has been shown to interact with RIT1[7] and CUL3.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000117153Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026455Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: KLHL12 kelch-like 12 (Drosophila)".
  7. ^ a b Rondou P, Haegeman G, Vanhoenacker P, Van Craenenbroeck K (April 2008). "BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase". The Journal of Biological Chemistry. 283 (17): 11083–96. doi:10.1074/jbc.M708473200. PMC 2431063. PMID 18303015.

Further reading

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