Khanyisile is a feminine given name, derived from the Nguni word khanya, meaning "light." Notable people with the name include:
- Khanyisile Mbau (born 1985), South African actress
- Khanyisile Motsa, South African humanitarian
- Khanyisile Litchfield-Tshabalala, South African navy admiral
This page or section lists people that share the same given name.
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