The kindling hypothesis of depression posits that each period of depression in someone with major depressive disorder (MDD) causes neurological changes that predispose the person to future episodes. While the first episode of depression is often triggered by major life events, future episodes are less likely to be tied to circumstantial factors.[1] There is some evidence to support the kindling hypothesis.[2]
References
edit- ^ Monroe, Scott M.; Harkness, Kate L. (2005). "Life Stress, the "Kindling" Hypothesis, and the Recurrence of Depression: Considerations From a Life Stress Perspective". Psychological Review. 112 (2): 417–445. doi:10.1037/0033-295X.112.2.417. PMID 15783292.
- ^ Rigoli, Francesco (17 November 2022). "When all glasses look half empty: a computational model of reference dependent evaluation to explain depression" (PDF). Journal of Cognitive Psychology. 34 (8): 1022–1031. doi:10.1080/20445911.2022.2107650. S2CID 251481438.