Klepač, Klepáč (Czech/Slovak feminine: Klepáčová), or Klepac is a surname of Slovene, Croatian, Czech, and Slovak origin. Notable people with the surname include:
- Andreja Klepač (born 1986), Slovenian tennis player
- Mihael Klepač (born 1997), Croatian footballer
- Peter Klepáč (born 1975), Slovak ice hockey player
- Eva Klepáčová (1933–2012), Czech actress