Kontoyiannis (Greek: Κοντογιάννης) is a Greek surname. Notable people with the surname include:
- Dimitrios Kontoyiannis (born 1963), Greek–American physician
- Ioannis Kontoyiannis (born 1972), Greek mathematician and information theorist
Kontoyiannis (Greek: Κοντογιάννης) is a Greek surname. Notable people with the surname include: