Lăcătuș or Lăcătușu is an occupational Romanian surname that means locksmith. It may refer to
- Izabela Lăcătuș (born 1976), Romanian artistic and aerobic gymnast
- Marius Lăcătuș (born 1964), Romanian football player
- Mihaela Lăcătuș (born 1981), Romanian boxer
- Constantin Lăcătușu (born 1961), Romanian mountain climber