L-glycol dehydrogenase

In enzymology, a L-glycol dehydrogenase (EC 1.1.1.185) is an enzyme that catalyzes the chemical reaction

L-glycol dehydrogenase
Identifiers
EC no.1.1.1.185
CAS no.77967-75-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
an L-glycol + NAD(P)+ a 2-hydroxycarbonyl compound + NAD(P)H + H+

The 3 substrates of this enzyme are L-glycol, NAD+, and NADP+, whereas its 4 products are 2-hydroxycarbonyl compound, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-glycol:NAD(P)+ oxidoreductase. Other names in common use include glycol (nicotinamide adenine dinucleotide (phosphate)), dehydrogenase, L-(+)-glycol:NAD(P)+ oxidoreductase, and L-glycol:NAD(P)+ dehydrogenase.

References

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  • Bernardo A, Burgos J, Martin R (1981). "Purification and some properties of L-glycol dehydrogenase from hen's muscle". Biochim. Biophys. Acta. 659 (1): 189–98. doi:10.1016/0005-2744(81)90283-7. PMID 7018582.