L25 ribosomal protein leader is a ribosomal protein leader involved in the ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal protein L25. Known Examples were predicted in Gammaproteobacteria with bioinformatic approaches.[1] or in Enterobacteria.[2] The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal protein L25 (rplY).[2][1]
| Ribosomal L25 leader | |
|---|---|
 Predicted secondary structure and sequence conservation of L25_leader. This picture was adapted from a previous publication. [1] | |
| Identifiers | |
| Symbol | L25 |
| Rfam | RF03131 |
| Other data | |
| RNA type | Cis-reg; leader |
| Domain(s) | Bacteria |
| PDB structures | PDBe |
See also
editReferences
edit- ^ a b c Eckert, I; Weinberg, Z (24 May 2020). "Discovery of 20 novel ribosomal leader candidates in bacteria and archaea". BMC Microbiology. 20 (130): 130. doi:10.1186/s12866-020-01823-6. PMC 7247131. PMID 32448158.
- ^ a b Aseev, LV; Bylinkina, NS; Boni, IV (2015). "Regulation of the rplY gene encoding 5S rRNA binding protein L25 in Escherichia coli and related bacteria". RNA. 20 (130): 851–61. doi:10.1261/rna.047381.114. PMC 4408793. PMID 25749694.
External links
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