LBU is a three-letter acronym that may refer to:
- Universities
- Leeds Beckett University in Leeds, England
- Loughborough University in Loughborough, England
- Louisiana Baptist University, an unaccredited Bible college in Louisiana, USA
- Lucian Blaga University of Sibiu in Sibiu, Romania
- Lumbini Buddhist University in Lumbini, Nepal
- Pennsylvania State University in Pennsylvania, USA, whose football program is sometimes referred to as Linebacker University
- Other
- Labuan Airport, Labuan, Malaysia airport code
- Labu language, ISO 639-3 language code
- Leaflet bomb unit, a type of cluster munition for dropping propaganda from aircraft