LETMD1

LETMD1
Identifiers
Aliases	LETMD1, 1110019O13Rik, HCCR-1, HCCR-2, HCCR1, HCRR-2, LETM1 domain containing 1
External IDs	MGI: 1915864; HomoloGene: 9128; GeneCards: LETMD1; OMA:LETMD1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	100,377,045 bp
RNA expression pattern
	n/a
	Top expressed in
	brown adipose tissue; ; ascending aorta; ; dentate gyrus of hippocampal formation granule cell; ; cumulus cell; ; lumbar spinal ganglion; ; adrenal gland; ; Rostral migratory stream; ; superior frontal gyrus; ; aortic valve; ; primary visual cortex;
	More reference expression data
Gene ontology
Molecular function	protein binding; ribosome binding;
Cellular component	mitochondrial outer membrane; membrane; integral component of membrane; nucleoplasm; mitochondrion; mitochondrial inner membrane;
Biological process	cellular metal ion homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	25875
	68614
	ENSG00000050426
	ENSMUSG00000037353
	Q6P1Q0
	Q924L1
NM_001024668; NM_001024669; NM_001024670; NM_001024671; NM_001243689;
	NM_001300765; NM_015416
	NM_134093; NM_001357982; NM_001357983; NM_001357984
NP_001230618; NP_001287694; NP_056231; NP_001338242; NP_001338245;
	NP_001338246; NP_001338248; NP_001338249; NP_001338250; NP_001338251; NP_001338252; NP_001338253; NP_001338254; NP_001338255; NP_001338256; NP_001338257; NP_001338259; NP_001338261; NP_001338262; NP_001338263; NP_001338264; NP_001338265; NP_001338266; NP_001338241; NP_001338244
	NP_598854; NP_001344911; NP_001344912; NP_001344913
	Wikidata
View/Edit Human	View/Edit Mouse

LETM1 domain-containing protein 1 is a protein that in humans is encoded by the LETMD1 gene.^[4]^[5]^[6]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037353 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ko J, Lee YH, Hwang SY, Lee YS, Shin SM, Hwang JH, Kim J, Kim YW, Jang SW, Ryoo ZY, Kim IK, Namkoong SE, Kim JW (Jul 2003). "Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization". Oncogene. 22 (30): 4679–4689. doi:10.1038/sj.onc.1206624. PMID 12879013.
^ Qi ZY, Li Y, Ying K, Wu CQ, Tang R, Zhou ZX, Chen ZP, Hui GZ, Xie Y (Jun 2002). "Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes". J Neurooncol. 56 (3): 197–208. doi:10.1023/A:1015079705841. PMID 12061725. S2CID 23878825.
^ "Entrez Gene: LETMD1 LETM1 domain containing 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ko J, Shin SM, Oh YM, et al. (2004). "Transgenic mouse model for breast cancer: induction of breast cancer in novel oncogene HCCR-2 transgenic mice". Oncogene. 23 (10): 1950–1953. doi:10.1038/sj.onc.1207356. PMID 14691448.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Jung SS, Park HS, Lee IJ, et al. (2006). "The HCCR oncoprotein as a biomarker for human breast cancer". Clin. Cancer Res. 11 (21): 7700–7708. doi:10.1158/1078-0432.CCR-04-2609. PMID 16278390.
Cho GW, Shin SM, Namkoong H, et al. (2007). "The phosphatidylinositol 3-kinase/Akt pathway regulates the HCCR-1 oncogene expression". Gene. 384: 18–26. doi:10.1016/j.gene.2006.07.006. PMID 16949218.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000037353 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12879013-4] Ko J, Lee YH, Hwang SY, Lee YS, Shin SM, Hwang JH, Kim J, Kim YW, Jang SW, Ryoo ZY, Kim IK, Namkoong SE, Kim JW (Jul 2003). "Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization". Oncogene. 22 (30): 4679–4689. doi:10.1038/sj.onc.1206624. PMID 12879013.

[pmid12061725-5] Qi ZY, Li Y, Ying K, Wu CQ, Tang R, Zhou ZX, Chen ZP, Hui GZ, Xie Y (Jun 2002). "Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes". J Neurooncol. 56 (3): 197–208. doi:10.1023/A:1015079705841. PMID 12061725. S2CID 23878825.

[entrez-6] "Entrez Gene: LETMD1 LETM1 domain containing 1".

[4]

[5]

[6]

[1]

[2]

[3]

LETMD1

References

Further reading