LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication. Data suggest that the LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene.[1]

References

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  1. ^ Haraldson K, Kashuba VI, Dmitriev AA, Senchenko VN, Kudryavtseva AV, Pavlova TV, Braga EA, Pronina IV, Kondratov AG, Rynditch AV, Lerman MI, Zabarovsky ER (2012). "LRRC3B is a gene frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication". Biochimie. 94 (9): 1151–1157. doi:10.1016/j.biochi.2012.01.019. PMID 22321817.