La Harpe is a surname. Notable people with the surname include:
- Amédée Emmanuel François Laharpe (1754–1796), French general and cousin of Frédéric-César
- Jean-Baptiste Bénard de la Harpe (1683–1765), French explorer
- Frédéric-César de La Harpe (1754–1838), Swiss politician and tutor to the Tsar of Russia
- Jean-François de La Harpe (1739–1803), French playwright, writer and critic