The lactis-plasmid RNA motif is a conserved RNA structure identified by bioinformatics.[1] The RNAs are restricted to lactic acid bacteria, and are especially common in Lactococcus lactis. They typically lie near to repB genes, and are almost found in plasmids. This data suggested that lactis-plasmid RNAs participate in the control of plasmid abundance.[2] However, many of the plasmids that carry lactis-plasmid RNAs also carry ctRNA-pND324 RNAs, which are involved in plasmid copy count regulation. Therefore lactis-plasmid RNAs might have a different function.
| lactis-plasmid RNA | |
|---|---|
 Consensus secondary structure of lactis-plasmid RNAs | |
| Identifiers | |
| Symbol | lactis-plasmid RNA |
| Rfam | RF01742 |
| Other data | |
| RNA type | sRNA |
| Domain(s) | lactic acid bacteria |
| PDB structures | PDBe |
See also
editReferences
edit- ^ Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
- ^ Kim K, Meyer RJ (October 1986). "Copy-number of broad host-range plasmid R1162 is regulated by a small RNA". Nucleic Acids Res. 14 (20): 8027–8046. doi:10.1093/nar/14.20.8027. PMC 311832. PMID 2430262.
External links
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