Lemonomycin is an antibiotic with the molecular formula C27H41N3O9 which is produced by the bacterium Streptomyces candidus.[1][2] Lemonomycin was first isolated in 1964[2] Lemonomycin has also shown activity against human colon tumor cells.[2]
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Other names
(–)-Lemonomycin
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3D model (JSmol)
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ChEBI | |
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PubChem CID
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Properties | |
C27H41N3O9 | |
Molar mass | 551.637 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Ashley, Eric R.; Cruz, Ernest G.; Stoltz, Brian M. (1 December 2003). "The Total Synthesis of (−)-Lemonomycin". Journal of the American Chemical Society. 125 (49): 15000–15001. doi:10.1021/ja039223q. PMID 14653730.
- ^ a b c Williams, Robert M. (2 December 2012). 19th International Congress on Heterocyclic Chemistry: Book of Abstracts. Newnes. p. 130. ISBN 978-0-08-098401-8.
Further reading
edit- Jiménez-Somarribas, Alberto; Williams, Robert M. (2 September 2013). "Synthetic studies on lemonomycin: construction of the tetracyclic core". Tetrahedron. 69 (35): 7505–7512. doi:10.1016/j.tet.2013.05.009. hdl:10217/80986. ISSN 0040-4020. PMC 4114395. PMID 25083002.
- Harmata, Michael (2012). Strategies and Tactics in Organic Synthesis. Academic Press. p. 353. ISBN 978-0-12-386540-3.
- Gholamzadeh, Parisa (14 January 2019). The Pictet–Spengler Reaction: A Powerful Strategy for the Synthesis of Heterocycles. Advances in Heterocyclic Chemistry. Vol. 127. Academic Press. p. 157. doi:10.1016/bs.aihch.2018.09.002. ISBN 978-0-12-817150-9. S2CID 104840386.