Lemonomycin is an antibiotic with the molecular formula C27H41N3O9 which is produced by the bacterium Streptomyces candidus.[1][2] Lemonomycin was first isolated in 1964[2] Lemonomycin has also shown activity against human colon tumor cells.[2]

Lemonomycin
Names
Other names
(–)-Lemonomycin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1S/C27H41N3O9/c1-11-21(31)13-8-16-20-14(26(34)35)7-15(28-20)25(33)30(16)17(19(13)22(32)23(11)37-6)10-38-18-9-27(3,36)24(29(4)5)12(2)39-18/h12,14-18,20,24-26,28,33-36H,7-10H2,1-6H3/t12-,14+,15-,16-,17-,18+,20+,24+,25-,27-/m0/s1
    Key: JXWCEWIDCYAQRW-RNWDBXQFSA-N
  • C[C@H]1[C@H]([C@@](C[C@@H](O1)OC[C@H]2C3=C(C[C@@H]4N2[C@H]([C@@H]5C[C@H]([C@H]4N5)C(O)O)O)C(=O)C(=C(C3=O)OC)C)(C)O)N(C)C
Properties
C27H41N3O9
Molar mass 551.637 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

edit
  1. ^ Ashley, Eric R.; Cruz, Ernest G.; Stoltz, Brian M. (1 December 2003). "The Total Synthesis of (−)-Lemonomycin". Journal of the American Chemical Society. 125 (49): 15000–15001. doi:10.1021/ja039223q. PMID 14653730.
  2. ^ a b c Williams, Robert M. (2 December 2012). 19th International Congress on Heterocyclic Chemistry: Book of Abstracts. Newnes. p. 130. ISBN 978-0-08-098401-8.

Further reading

edit