Lesia is a feminine given name. Notable people with the name include:
- Lesia Dychko (born 1939), Ukrainian music educator and composer
- Lesia Liss (born 1966), American politician
- Lesia Tsurenko (born 1989), Ukrainian tennis player
- Lesia Valadzenkava (born 1991), Belarusian ice dancer
- Lesia Vasylenko (born 1987), Ukrainian lawyer and politician
Other uses:
- Lesia (plant), a genus of plants in the family Gesneriaceae
- LESIA, a French space and astrophysics instrumentation research laboratory