Linda Karen Medlin is a molecular biologist known for her work on diatoms. She is an elected member of the Norwegian Academy of Science and Letters.
Linda Medlin | |
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Alma mater | Texas A&M University |
Scientific career | |
Thesis | Community analysis of epiphytic diatoms from selected species of macroalgae collected along the Texas coast of the Gulf of Mexico (1983) |
Education and career
editMedlin has a B.S. from the University of Texas at Austin (1970),[1] and an M.S. (1977)[2] and a Ph.D.(1983)[1] from Texas A&M University. She has worked at the Alfred-Wegener-Institute in Germany (1991-2009), Observatoire océanologique de Banyuls-sur-Mer in France (2009-2013), and the company Microbia Environment in France (2013-2016).[1] As of 2008, she is an associate research fellow at the Marine Biological Association.[3]
Research
editMedlin's early work was with Greta Fryxell on the taxonomy of diatoms.[4][5] She is known for her work on applying molecular tools to the study of phytoplankton, and she was the first to develop primers for polymerase chain reaction that targeted eukaryotic organisms,[6] She applied this tool to taxonomic studies of multiple species of phytoplankton cultured in the laboratory.[7][8][9] Her work extended into the ocean where she examined the diversity of phytoplankton in different regions including the Pacific Ocean,[10] Antarctica,[11] and the time series from the German research station at Heligoland.[12] Through the application of molecular tools, Medlin was able to define species differences in coccolithophores[13] and examine the evolution of diatoms.[14] In 2007, Medlin led the group who discovered a new lineage within photosynthetic eukaryotic organisms, the picobiliphytes,[15] and then presented the first cultured strain in 2013 but the group is not photosynthetic but heterotrophic and feeds primarily on cryptomonads and may keep their plastids, hence the chartarcteristic pigments first associated with the group..[16] More recently. Medlin has worked on the phytoplankton within harmful algal blooms and improving methods for monitoring such blooms using DNA barcodes as probes in electrochemical biosensors.[17][18][19]
Selected publications
edit- Medlin, Linda; Elwood, Hille J.; Stickel, Shawn; Sogin, Mitchell L. (1988-11-30). "The characterization of enzymatically amplified eukaryotic 16S-like rRNA-coding regions". Gene. 71 (2): 491–499. doi:10.1016/0378-1119(88)90066-2. ISSN 0378-1119. PMID 3224833.
- Bowler, Chris; Allen, Andrew E. (2008). "The Phaeodactylum genome reveals the evolutionary history of diatom genomes". Nature. 456 (7219): 239–244. Bibcode:2008Natur.456..239B. doi:10.1038/nature07410. ISSN 0028-0836. PMID 18923393. S2CID 4415177.
- Sims, Patricia A.; Mann, David G.; Medlin, Linda K. (2006-07-01). "Evolution of the diatoms: insights from fossil, biological and molecular data". Phycologia. 45 (4): 361–402. Bibcode:2006Phyco..45..361S. doi:10.2216/05-22.1. ISSN 0031-8884. S2CID 55058077.
- Medlin, Linda K.; Kaczmarska, Irena (2004-05-01). "Evolution of the diatoms: V. Morphological and cytological support for the major clades and a taxonomic revision". Phycologia. 43 (3): 245–270. Bibcode:2004Phyco..43..245M. doi:10.2216/i0031-8884-43-3-245.1. ISSN 0031-8884. S2CID 83631828.
- Medlin, Linda; Simon, Nathalie (1998), Cooksey, Keith E. (ed.), "Phylogenetic Analysis of Marine Phytoplankton", Molecular Approaches to the Study of the Ocean, Dordrecht: Springer Netherlands, pp. 161–186, doi:10.1007/978-94-011-4928-0_7, ISBN 978-94-010-6067-7
Awards and honors
editMedlin was elected foreign member of Norwegian Academy of Science and Letters in 1998.[20] Four of Medlin's papers have received awards, one paper[21] received the Luigi Provasoli award from the Phycological Society of America,[22] and three papers[14][23] have received the Tyge Christensen Award from the International Phycological Society.[24] Medlin received the Yasumoto Lifetime Achievement Award from the International Society for the Study of Harmful Algae in 2021.[25]
References
edit- ^ a b c "Medlin CV" (PDF). Retrieved October 31, 2021.
- ^ Medlin, Linda Karen (1977). Light and electron microscopic studies of the nanobenthic diatom, Nitzschia ovalis Arnott, Section Lanceolatae, as compared to related forms, and the effect of temperature and salinity on its growth rate (Thesis). College Station, Tex.: Medlin. OCLC 3306295.
- ^ "| Marine Biological Association". www.mba.ac.uk. Retrieved 2021-11-01.
- ^ Fryxell, Greta A.; Laboratoire de cryptogamie, Paris; Association des amis des cryptogames, France (1981). "Chain forming diatoms: evidence of parallel evolution in Chaetoceros". Cryptogamie. Algologie. 2. Paris: ADAC: 3–29. doi:10.5962/p.309011.
- ^ Medlin, Linda K.; Fryxell, Greta A. (1984). "Structure, Life History and Systematics of Rhoicosphenia (bacillariophyta). Iv. Correlation of Size Reduction with Changes in Valve Morphology of Rh. Genuflexa1". Journal of Phycology. 20 (1): 101–108. Bibcode:1984JPcgy..20..101M. doi:10.1111/j.0022-3646.1984.00101.x. ISSN 1529-8817. S2CID 85431562.
- ^ Medlin, Linda; Elwood, Hille J.; Stickel, Shawn; Sogin, Mitchell L. (1988-11-30). "The characterization of enzymatically amplified eukaryotic 16S-like rRNA-coding regions". Gene. 71 (2): 491–499. doi:10.1016/0378-1119(88)90066-2. ISSN 0378-1119. PMID 3224833.
- ^ Medlin, Linda K.; Elwood, Hille J.; Stickel, Shawn; Sogin, Mitchell L. (1991). "Morphological and Genetic Variation Within the Diatom Skeletonema costatum (bacillariophyta): Evidence for a New Species, Skeletonema pseudocostatum1". Journal of Phycology. 27 (4): 514–524. Bibcode:1991JPcgy..27..514M. doi:10.1111/j.0022-3646.1991.00514.x. ISSN 1529-8817. S2CID 84971128.
- ^ Medlin, L. K.; Lange, M.; Baumann, M. E. M. (1994-05-01). "Genetic differentiation among three colony-forming species of Phaeocystis: further evidence for the phylogeny of the Prymnesiophyta". Phycologia. 33 (3): 199–212. Bibcode:1994Phyco..33..199M. doi:10.2216/i0031-8884-33-3-199.1. ISSN 0031-8884.
- ^ Medlin, L. K.; Barker, G. L. A.; Campbell, L.; Green, J. C.; Hayes, P. K.; Marie, D.; Wrieden, S.; Vaulot, D. (1996-10-01). "Genetic characterisation of Emiliania huxleyi (Haptophyta)". Journal of Marine Systems. EHUX (Emiliania huxleyi). 9 (1): 13–31. Bibcode:1996JMS.....9...13M. doi:10.1016/0924-7963(96)00013-9. ISSN 0924-7963.
- ^ Staay, Seung Yeo Moon-van der; Staay, Georg W. M. van der; Guillou, Laure; Vaulot, Daniel; Claustre, Herveé; Medlin, Linda K. (2000). "Abundance and diversity of prymnesiophytes in the picoplankton coμmunity from the equatorial Pacific Ocean inferred from 18S rDNA sequences". Limnology and Oceanography. 45 (1): 98–109. Bibcode:2000LimOc..45...98M. doi:10.4319/lo.2000.45.1.0098. ISSN 1939-5590. S2CID 86227557.
- ^ Medlin, Linda K.; Lange, Martin; Nöthig, Eva-Maria (2000). "Genetic diversity in the marine phytoplankton: a review and a consideration of Antarctic phytoplankton". Antarctic Science. 12 (3): 325–333. Bibcode:2000AntSc..12..325M. doi:10.1017/S0954102000000389. ISSN 1365-2079. S2CID 85185098.
- ^ Medlin, L. K.; Metfies, K.; Mehl, H.; Wiltshire, Karen; Valentin, K. (2006). "Picoeukaryotic Plankton Diversity at the Helgoland Time Series Site as Assessed by Three Molecular Methods". Microbial Ecology. 52 (1): 53–71. Bibcode:2006MicEc..52...53M. doi:10.1007/s00248-005-0062-x. ISSN 0095-3628. PMID 16703447. S2CID 23906313.
- ^ Sáez, Alberto G.; Probert, Ian; Geisen, Markus; Quinn, Patrick; Young, Jeremy R.; Medlin, Linda K. (2003-06-10). "Pseudo-cryptic speciation in coccolithophores". Proceedings of the National Academy of Sciences. 100 (12): 7163–7168. Bibcode:2003PNAS..100.7163S. doi:10.1073/pnas.1132069100. ISSN 0027-8424. PMC 165847. PMID 12759476.
- ^ a b Medlin, Linda K.; Kaczmarska, Irena (2004-05-01). "Evolution of the diatoms: V. Morphological and cytological support for the major clades and a taxonomic revision". Phycologia. 43 (3): 245–270. Bibcode:2004Phyco..43..245M. doi:10.2216/i0031-8884-43-3-245.1. ISSN 0031-8884. S2CID 83631828.
- ^ Not, Fabrice; Valentin, Klaus; Romari, Khadidja; Lovejoy, Connie; Massana, Ramon; Töbe, Kerstin; Vaulot, Daniel; Medlin, Linda K. (2007-01-12). "Picobiliphytes: A Marine Picoplanktonic Algal Group with Unknown Affinities to Other Eukaryotes". Science. 315 (5809): 253–255. Bibcode:2007Sci...315..253N. doi:10.1126/science.1136264. PMID 17218530. S2CID 22285394.
- ^ Seenivasan, Ramkumar; Sausen, Nicole; Medlin, Linda K.; Melkonian, Michael (2013-03-26). "Picomonas judraskeda Gen. Et Sp. Nov.: The First Identified Member of the Picozoa Phylum Nov., a Widespread Group of Picoeukaryotes, Formerly Known as 'Picobiliphytes'". PLOS ONE. 8 (3): e59565. Bibcode:2013PLoSO...859565S. doi:10.1371/journal.pone.0059565. ISSN 1932-6203. PMC 3608682. PMID 23555709.
- ^ Taylor, Joe D.; Kegel, Jessica U.; Lewis, Jane M.; Medlin, Linda K. (2014-07-01). "Validation of the detection of Alexandrium species using specific RNA probes tested in a microarray format: Calibration of signal using variability of RNA content with environmental conditions" (PDF). Harmful Algae. 37: 17–27. Bibcode:2014HAlga..37...17T. doi:10.1016/j.hal.2014.05.001. ISSN 1568-9883.
- ^ Medlin, Linda K.; Orozco, Jahir (2017). "Molecular Techniques for the Detection of Organisms in Aquatic Environments, with Emphasis on Harmful Algal Bloom Species". Sensors. 17 (5): 1184. Bibcode:2017Senso..17.1184M. doi:10.3390/s17051184. PMC 5470929. PMID 28531156.
- ^ Gescher, Christine; Metfies, Katja; Medlin, Linda K. (2008-06-01). "The ALEX CHIP—Development of a DNA chip for identification and monitoring of Alexandrium". Harmful Algae. 7 (4): 485–494. Bibcode:2008HAlga...7..485G. doi:10.1016/j.hal.2007.11.001. ISSN 1568-9883.
- ^ "Artikkel: Group 6: Cellular and Molecular biology". Norwegian Academy of Science and Letters. Retrieved 2021-11-01.
- ^ Sarno, Diana; Kooistra, Wiebe H. C. F.; Medlin, Linda K.; Percopo, Isabella; Zingone, Adriana (2005). "Diversity in the Genus Skeletonema (bacillariophyceae). Ii. an Assessment of the Taxonomy of S. Costatum-Like Species with the Description of Four New Species1" (PDF). Journal of Phycology. 41 (1): 151–176. Bibcode:2005JPcgy..41..151S. doi:10.1111/j.1529-8817.2005.04067.x. ISSN 1529-8817. S2CID 53679188.
- ^ "Provasoli Award". Phycological Society of America. Retrieved 2021-11-01.
- ^ Sims, Patricia A.; Mann, David G.; Medlin, Linda K. (2006-07-01). "Evolution of the diatoms: insights from fossil, biological and molecular data". Phycologia. 45 (4): 361–402. Bibcode:2006Phyco..45..361S. doi:10.2216/05-22.1. ISSN 0031-8884. S2CID 55058077.url=https://doi.org/10.2216/i0031-8884-39-1-19.1
- ^ "International Phycological Society - Past Winners Tyge Christensen Prize". intphycsociety.org.
- ^ "Pioneering MBA Associate Research Fellow awarded lifetime achievement award". October 13, 2021. Archived from the original on November 4, 2021.
External links
edit- Linda Medlin publications indexed by Google Scholar