This is a list of films which have placed number one at the weekend box office in Colombia during 2011.
| # | Date | Film | Gross |
|---|---|---|---|
| 1 | January 9, 2011 | Tangled | $1,219,266 |
| 2 | January 16, 2011 | Tangled | $1,075,946 |
| 3 | January 23, 2011 | Tangled | $641,580 |
| 4 | January 30, 2011 | Yogi Bear | $700,713 |
| 5 | February 6, 2011 | Yogi Bear | $503,963 |
| 6 | February 13, 2011 | Yogi Bear | $354,727 |
| 7 | February 20, 2011 | The Rite | $422,680 |
| 8 | February 27, 2011 | The Rite | $328,368 |
| 9 | March 6, 2011 | Rango | $396,261 |
| 10 | March 13, 2011 | Battle: Los Angeles | $325,654 |
| 12 | March 20, 2011 | Battle: Los Angeles | $245,428 |
| 13 | March 27, 2011 | Big Mommas: Like Father, Like Son | $203,100 |
| 14 | April 3, 2011 | Just Go with It | $205,129 |
| 15 | April 10, 2011 | Rio | $1,423,780 |
| 16 | April 17, 2011 | Rio | $1,304,273 |
| 17 | April 24, 2011 | Rio | $1,187,984 |
| 18 | May 1, 2011 | Thor | $930,674 |
| 19 | May 8, 2011 | Fast Five | $738,817 |
| 20 | May 15, 2011 | Fast Five | $749,144 |
| 21 | May 22, 2011 | Pirates of the Caribbean: On Stranger Tides | $1,972,961 |
| 22 | May 29, 2011 | Pirates of the Caribbean: On Stranger Tides | $1,384,949 |
| 23 | June 5, 2011 | Pirates of the Caribbean: On Stranger Tides | $971,555 |
| 24 | June 12, 2011 | Kung Fu Panda 2 | $1,721,349 |
| 25 | June 19, 2011 | Kung Fu Panda 2 | $979,105 |
| 26 | June 26, 2011 | Cars 2 | $1,484,727 |
| 27 | July 3, 2011 | Transformers: Dark of the Moon | $1,696,863 |
| 28 | July 10, 2011 | Transformers: Dark of the Moon | $1,167,463 |
| 29 | July 17, 2011 | Harry Potter and the Deathly Hallows – Part 2 | $2,127,746 |
| 30 | July 24, 2011 | Harry Potter and the Deathly Hallows – Part 2 | $1,007,427 |
| 31 | July 31, 2011 | Captain America: The First Avenger | $1,159,116 |
| 32 | August 7, 2011 | The Smurfs | $1,717,952 |
| 33 | August 14, 2011 | The Smurfs | $1,545,925 |
| 34 | August 21, 2011 | The Smurfs | $1,053,469 |
| 35 | August 28, 2011 | The Smurfs | $810,883 |
| 36 | September 4, 2011 | Final Destination 5 | $614,748 |
| 37 | September 11, 2011 | Rise of the Planet of the Apes | $646,210 |
| 38 | September 18, 2011 | Rise of the Planet of the Apes | $537,291 |
| 39 | September 25, 2011 | Rise of the Planet of the Apes | $373,378 |
| 40 | October 2, 2011 | Rise of the Planet of the Apes | $279,941 |
| 41 | October 9, 2011 | Real Steel | $593,899 |
| 42 | October 16, 2011 | Real Steel | $589,412 |
| 43 | October 23, 2011 | Paranormal Activity 3 | $372,263 |
| 44 | November 6, 2011 | Real Steel | $230,161 |
| 45 | November 13, 2011 | Jack and Jill | $202,363 |
| 46 | November 20, 2011 | The Twilight Saga: Breaking Dawn - Part 1 | $1,265,785 |
| 47 | November 27, 2011 | The Twilight Saga: Breaking Dawn - Part 1 | $617,198 |
| 48 | December 4, 2011 | Arthur Christmas | $380,659 |
| 49 | December 11, 2011 | Puss in Boots | $1,866,890 |
| 50 | December 18, 2011 | Puss in Boots | $973,546 |
| 51 | December 25, 2011 | Mission: Impossible – Ghost Protocol | $446,196 |
| 52 | January 1, 2012 | Puss in Boots | $395,077 |