This is a list of the Dutch Top 40 number-one singles of 2008.
| Issue date | Song | Artist(s) |
|---|---|---|
| 5 January | "Apologize" | Timbaland presents OneRepublic |
| 12 January | ||
| 19 January | ||
| 26 January | "Valerie" | Mark Ronson featuring Amy Winehouse |
| 2 February | ||
| 9 February | ||
| 16 February | ||
| 23 February | "Bleeding Love" | Leona Lewis |
| 1 March | ||
| 8 March | ||
| 15 March | "Hello World" | Nikki |
| 22 March | ||
| 29 March | ||
| 5 April | "Mercy" | Duffy |
| 12 April | ||
| 19 April | "Shot of a Gun" | Kane |
| 26 April | ||
| 3 May | "Wit Licht" | Marco Borsato |
| 10 May | ||
| 17 May | ||
| 24 May | "4 Minutes" | Madonna featuring Justin Timberlake & Timbaland |
| 31 May | ||
| 7 June | "This Is the Life" | Amy Macdonald |
| 14 June | ||
| 21 June | "Viva Hollandia" (EK Versie) | Wolter Kroes |
| 28 June | ||
| 5 July | "Can You Hear Me" | Enrique Iglesias |
| 12 July | ||
| 19 July | "Give It 2 Me" | Madonna |
| 26 July | ||
| 2 August | ||
| 9 August | ||
| 16 August | ||
| 23 August | ||
| 30 August | "Stop de Tijd" | Marco Borsato |
| 6 September | ||
| 13 September | ||
| 20 September | "I Kissed a Girl" | Katy Perry |
| 27 September | ||
| 4 October | "Viva la Vida" | Coldplay |
| 11 October | ||
| 18 October | ||
| 25 October | "Show Me Love 2008" | Robin S. |
| 1 November | ||
| 8 November | ||
| 15 November | "Dochters" | Marco Borsato |
| 22 November | ||
| 29 November | ||
| 6 December | "If I Were a Boy" | Beyoncé |
| 13 December | ||
| 20 December | ||
| 27 December |
Number-one artists
edit| Position | Artist | Weeks #1 |
|---|---|---|
| 1 | Marco Borsato | 9 |
| 2 | Madonna | 8 |
| 3 | Timbaland | 5 |
| 4 | Mark Ronson | 4 |
| 4 | Amy Winehouse | 4 |
| 3 | Robbie Williams | 4 |
| 3 | Beyoncé | 4 |
| 4 | OneRepublic | 3 |
| 4 | Leona Lewis | 3 |
| 4 | Nikki | 3 |
| 4 | Coldplay | 3 |
| 4 | Robin S. | 3 |
| 5 | Duffy | 2 |
| 5 | Kane | 2 |
| 5 | Justin Timberlake | 2 |
| 5 | Amy Macdonald | 2 |
| 5 | Wolter Kroes | 2 |
| 5 | Enrique Iglesias | 2 |
| 5 | Katy Perry | 2 |